Browsing by Subject "Particle depositions"

Now showing items 1-4 of 4

    • Conference Object  

      CFD modeling of turbulent flow and particle deposition in human lungs 

      Radhakrishnan, H.; Kassinos, Stavros C. (Affiliation: UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusCorrespondence Address: Radhakrishnan, H.UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprusemail: hariradh@ucy.ac.cy, 2009)
      Understanding transport and deposition of inhaled particles in the human airways plays a crucial role in the targeted therapy of pulmonary diseases, and the administration of inhaled medicines. Numerous researchers have ...
    • Conference Object  

      The effect of flow rate, head position, and inhaler orientation on the airflow and particle deposition in an mri-based mouth-throat geometry 

      Stylianou, F. S.; Angeli, S.; Kassinos, Stavros C.; Svensson, M. (International Symposium on Turbulence and Shear Flow Phenomena, TSFP10, 2017)
      The mouth-throat plays a key role in the administration of inhaled medicines. It is an area of intense filtration, where an unacceptably high fraction of the released drug dose is deposited and thus wasted. Due to the ...
    • Article  

      In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways 

      Koullapis, P. G.; Nicolaou, L.; Kassinos, Stavros C. (2018)
      Regional deposition of inhaled medicines is a valuable metric of effectiveness in drug delivery applications to the lung. In silico methods are now emerging as a valuable tool for the detailed description of localized ...
    • Conference Object  

      Numerical modeling of turbulent airflow and particle deposition in a bifurcating airway model 

      Radhakrishnan, H.; Kassinos, Stavros C. (Affiliation: UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, CyprusCorrespondence Address: Radhakrishnan, H.UCY-CompSci Computational Sciences Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus, 2009)
      Understanding transport and deposition of inhaled particles in the human airways plays a crucial role in the targeted therapy of pulmonary diseases, and the administration of inhaled medicines. Numerous researchers have ...